Above are the results of unscrambling all the words that contain issue. Using the word generator and word unscrambler for the letters I S S U E, we unscrambled the letters to create a list of all the words found in Scrabble, Words with Friends, and Text Twist. We found a total of 15 words that contain the letters in issue. Click these words to find out how many points they are worth, their definitions, and all the other words that can be made by unscrambling the letters from these words. If one or more words can be unscrambled with all the letters entered plus one new letter, then they will also be displayed.